Blar i NTNU Open på forfatter "Omtvedt, Line Aanerud"
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Alginate hydrogels functionalized with β-cyclodextrin as a local paclitaxel delivery system
Omtvedt, Line Aanerud; Kristiansen, Kåre Andre; Strand, Wenche Iren; Aachmann, Finn Lillelund; Strand, Berit Løkensgard; Zaytseva-Zotova, Daria Sergeevna (Journal article, 2021)Modification of drug delivery materials with beta-cyclodextrins (β-CyD) is known to increase solubility of poorly water-soluble drugs, protect drugs from degradation and sustain release. In this study, we developed a ... -
Combining Functionality of Polysaccharides for Drug Delivery Applications - A Study of CyD-Grafted Alginates
Omtvedt, Line Aanerud (Doctoral theses at NTNU;2021:342, Doctoral thesis, 2021-11)The biopolymer alginate has a vast potential for use within biomedical applications largely due to its ability to form ionically crosslinked hydrogels under gentle conditions. Furthermore, the versatile ways the polymer ... -
Efficient Grafting of Cyclodextrin to Alginate and Performance of the Hydrogel for Release of Model Drug
Omtvedt, Line Aanerud; Dalheim, Marianne Øksnes; Nielsen, Thorbjørn T.; Larsen, Kim; Strand, Berit Løkensgard; Aachmann, Finn Lillelund (Journal article; Peer reviewed, 2019)Controlling the rate of release of molecules from a hydrogel is of high interest for various drug delivery systems and medical devices. A strategy to alter the release profiles of soluble and poorly soluble active ingredients ... -
Mechanical Properties of Ca-Saturated Hydrogels with Functionalized Alginate
Dalheim, Marianne Øksnes; Omtvedt, Line Aanerud; Bjørge, Isabel M.; Akbarzadeh, Anita; Mano, Joao F.; Aachmann, Finn Lillelund; Strand, Berit Løkensgard (Journal article; Peer reviewed, 2019)In this work, the mechanical properties and stability of alginate hydrogels containing functionalized alginates (peptide and β-cyclodextrin) were studied. There is an increasing interest in the modification of alginates ...